The blood-brain barrier: an engineering perspective

The blood-brain barrier: an engineering perspective

It has been more than 100 years since Paul Ehrlich reported that various water-soluble dyes injected into the circulation did not enter the brain. Since Ehrlich's first experiments, only a small number of molecules, such as alcohol and caffeine have been found to cross the blood-brain barrier, and this selective permeability remains the major roadblock to treatment of many central nervous syste...

Engineering the human blood-brain barrier in vitro

The blood-brain barrier (BBB) is the interface between the vasculature and the brain, regulating molecular and cellular transport into the brain. Endothelial cells (ECs) that form the capillary walls constitute the physical barrier but are dependent on interactions with other cell types. In vitro models are widely used in BBB research for mechanistic studies and drug screening. Current models h...

Brain Tumors: An Engineering Perspective

With the rapid growth in technical evolution, medical field is growing like anything. For making good sound we need cooperation from both hands. In this manner, now a day’s medical and engineering technology, both are joined together and developing new innovations in medical field. These innovations are enlightening the life of human by providing proper treatment. Medical field reached a tremen...

Editorial: Neurotechnology: An Engineering Perspective

P45: The Role of Blood-Brain Barrier Breakdown Following Traumatic Brain in Post-Traumatic Epilepsy

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